Cancer is a broad group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. These abnormal cells can form masses of tissue called tumors, although not all cancers form tumors. Cancer can affect any part of the body, and there are more than 100 different types of cancer, each classified by the type of the cell that is initially affected.
Overview
In a healthy body, cells grow, divide, and die in an orderly way. However, in cancer, this normal process is disrupted. Cells continue to grow and divide uncontrollably, and instead of dying when they should, they accumulate and may form a mass of tissue called a tumor. Tumors can be either benign (non-cancerous) or malignant (cancerous). Benign tumors do not spread to other parts of the body, but malignant tumors can invade nearby tissues and spread to distant organs through the blood and lymphatic systems, a process known as metastasis.
Causes and Risk Factors
Cancer is caused by changes (mutations) to the DNA within cells. The DNA inside a cell is organized into many individual genes, which carry instructions for how the cells should grow, divide, and die. When Genes are mutated, these instructions can be disrupted, leading to abnormal cell behavior. Factors that can contribute to cancer development include:
- Genetic Factors: Inherited mutations can disease the risk of certain cancers, such as breast, ovarian, and colon cancers.
- Lifestyle Factors: Diet, physical activity, obesity, and alcohol consumption are known to influence cancer risk.
- Environmental factors: Exposure to carcinogens such as tobacco smoke, radiation, chemicals, and certain viruses can cause cancer.
- Age: The risk of cancer generally increases with age, as the accumulation of genetic over time can lead to cancer.
Types of Cancer
Some of the most common types of cancer include:
- Carcinoma: Cancer that begins in the skin or in tissues that line or cover internal organs. This is the most common type of cancer and includes lung, breast, colon, and prostate cancers.
- Sarcoma: Cancer that starts in bone, cartilage, fat, muscle, or other connective tissues.
- Leukemia: Cancer of the blood-forming tissues, such as the bone marrow, leading to abnormal white blood cell production.
- Lymphoma and Myeloma: Cancer that begin in the cells of the immune system.
- Central Nervous System Cancers that start in the brain and spinal cord.
Symptoms
- Unexpected weight loss
- Fatigue
- Persistent pain
- Changes in the skin (such as yellowing, darkening, or redness)
- Persistent cough or hoarseness
- Unexplained bleeding or bruising
Diagnosis
- Imagining Tests: X-ray, CT scans, MRI, and PET scans to detect abnormal growths.
- Biopsy: A sample of tissue is taken from the suspected tumor to examine under a microscope.
- Blood Tests: Some cancers produce substances in the blood called tumor markers that may help diagnose cancer.
Treatment
- Surgery: Removal of the tumor and surrounding tissue.
- Radiation Therapy: The use of high-energy radiation to kill cancer cells or shrink tumors.
- Chemotherapy: The use of drugs to kill cancer cells or stop them from growing.
- Immunotherapy: Treatment that helps the immune system fight cancer.
- Targeted Therapy: Drugs that target specific genes or proteins involved in cancer growth and spread.
- Hormone Therapy: Used to treat cancers that are hormone-sensitive, such as breast and prostate cancers.
Prevention
- Avoiding tobacco: Smoking is a major cause of cancer, especially lung cancer.
- Healthy diet: Eating a balanced diet with plenty of fruits and vegetables can lower cancer risk.
- Regular exercise: Physical activity can help maintain a healthy weight and lower the risk of certain cancers.
- Limiting alcohol: Reducing alcohol intake can lower the risk of cancers such as liver, breast, and colon cancer.
- Sun protection: Wearing sunscreen and avoiding excessive sun exposure can reduce the risk of skin cancer.
- Vaccinations: Vaccines such as the human papillomavirus (HPV) vaccine can help prevent certain types of cancer.
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